TBOPP
TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 μM. TBOPP exhibits anti-tumor activity.
Supplier | Selleck Chemicals |
---|---|
Product # | S0978 |
Sku # | S0978-10mM/1mL |
Pricing | 10mM/1mL, $570.00 |