Exherin
| Supplier | Creative Peptides |
|---|---|
| Product # | HB00096 |
| CAS # | 229971-81-7 |
| Pricing | Inquire |
| MolecularFormula | C22H34N8O6S2 |
| MolecularWeight | 570.69 |
| Storage | Desiccate at -20°C |
| ShippingCondition | Room temperature in continental US; may vary elsewhere. |
| Explanation | ADH-1, an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion. |
| Activity | Antagonist |
| Solubility | Soluble to 2.2 mg/mL in DMSO |
| BiologicalActivity | Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. |