Arachidonoyl amide
Arachidonamide (AEA) is a weak cannabinoid CB1 and CB2 agonist. Arachidonamide was hydrolyzed by FAAH more effectively than AEA but exhibited significantly weaker binding to the human CB1 receptor with a Ki of 9.6 μM. AEA also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 µM. Arachidonamide are found to be the best substrates for anandamide amidohydrolase (AAH) with relative rates of hydrolysis about twice that of anandamide.
| Supplier | BOC Sciences |
|---|---|
| Product # | 85146-53-8 |
| Pricing | Inquire |
| Cas | 85146-53-8 |
| Molecular Weight | 303.5 |
| Molecular Formula | C20H33NO |
| Canonical SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N |