| Supplier |
Creative Peptides |
| Product # |
R1763 |
| CAS # |
581-05-5 |
| Pricing |
Inquire
|
| Synonyms |
α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
|
| MolecularFormula |
C77H109N21O19S
|
| MolecularWeight |
1664.88
|
| Sequence |
- One Letter Code: Ac-SYSMEHFRWGKPV-NH2
- three Letter Code: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
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| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
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| Explanation |
α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
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| BiologicalActivity |
Endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-α, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration.
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