Methotrexate disodium

Supplier MedChemExpress
Product # HY-14519A-10 mM * 1 mL
CAS # 7413-34-5
Pricing 10 mM * 1 mL, USD $66.0
Synonyms Amethopterin disodium; CL14377 disodium; WR19039 disodium
MWt 498.4
Formula C₂₀H₂₀N₈Na₂O₅
Biological Activity Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia)[1][2][3].
Purity 98.26%
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