KP-457

KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17 with IC50 of 11.1 nM/L (cell-free assay). It also cleaves various molecules such as GPIbα, GPV, and TNF-α.

• Supplier: Selleck Chemicals
• Product #: E1386
• Sku #: E1386-5mg