CMLD-2

Supplier MedChemExpress
Product # HY-124828-5 mg
CAS # 958843-91-9
Pricing 5 mg, USD $300.0
Biological Activity CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2].
Purity 98.59%
MWt 513.58
Formula C₃₁H₃₁NO₆
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