Human Anti-KDR Recombinant Antibody (clone mAb6.64)
Recombinant Chimeric (Human/Mouse) Antibody (mAb6.64) is capable of binding to VEGFR2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-VEGFR2 mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-VEGFR2 proteins mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The antibody bind at opposite ends of VEGFR2 domain 3 and prevent receptor dimerization by perturbing the domain 3 : domain 4 interface.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABC-204 |
| Pricing | Inquiry |
| Host | Human |
| Target | KDR |
| Species Reactivity | Human |
| Type | Chimeric (mouse/human) IgG |
| Applications | ELISA, Block |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |