(5Z,2E)-CU-3

Supplier MedChemExpress
Product # HY-121638A-10 mM * 1 mL
CAS # 1815598-71-0
Pricing 10 mM * 1 mL, USD $220.0
Biological Activity (5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells[1].
Purity 98.04%
MWt 392.47
Formula C₁₆H₁₂N₂O₄S₃
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