Anti-Human ERBB3 Therapeutic Antibody (Elgemtumab)
Recombinant monoclonal antibody to ERBB3. Elgemtumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, head and neck. It binds to and locks HER3 in the inactive conformation and does not interfere with its interaction with neuregulin (NRG). The inactivated form of HER3 blocks the PI3K/Akt signaling pathway, thereby inhibiting cellular proliferation in HER2 or NRG expressing tumor cells.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-422CQ |
| Pricing | Inquiry |
| Host | Human |
| Target | ERBB3 |
| Species Reactivity | Human |
| Type | IgG1, κ |
| Applications | Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Blocking |
| Storage | Store at -20°C for long-term storage. Avoid freeze/thaw cycles. |