K-975
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-138565-10 mg |
| CAS # | 2563855-03-6 |
| Pricing | 10 mg, USD $350.0 |
| Biological Activity | K-975 is a potent, selective and orally active TEAD inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma[1]. |
| Purity | 98.55% |
| MWt | 287.74 |
| Formula | C₁₆H₁₄ClNO₂ |