3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea
3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea is a Rho kinase (ROCK) inhibitor. It had excellent enzyme and cellular potency, high kinase selectivity, high aqueous solubility, good porcine corneal penetration, and appropriate DMPK profiles for topical applications as antiglaucoma therapeutics.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1225199-26-7 |
| Pricing | Inquire |
| Cas | 1225199-26-7 |
| Molecular Weight | 449.55 |
| Molecular Formula | C25H31N5O3 |
| Canonical SMILES | CN(CC1=CC(=CC=C1)OC)C(=O)NC2=C(C=C(C=C2)C3=CNN=C3)OCCN4CCCC4 |