Combretastatin A-1 Phosphate Tetrasodium

Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 Phosphate Tetrasodium inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 Phosphate Tetrasodium exhibits anti-tumor and anti-vascular effects.

• Supplier: CD BioSciences
• Product #: CIA-11284