Sunitinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10255A-10 mM * 1 mL |
| CAS # | 557795-19-4 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | SU 11248 |
| MWt | 398.47 |
| Formula | C₂₂H₂₇FN₄O₂ |
| Biological Activity | Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. |
| Purity | ≥98.0% |