RORγt Inverse agonist 10
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133552 |
| CAS # | 2413986-35-1 |
| Pricing | inquire |
| Biological Activity | RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R[1] |
| MWt | 572.5 |
| Formula | C₂₅H₂₆F₆N₆O₃ |