PF-543 hydrochloride

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PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.

Supplier	Selleck Chemicals
Product #	S7177
Sku #	S7177-10mM/1mL
Pricing	10mM/1mL, $117.00

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