Stephacidin B
Stephacidin B is a fungal metabolite originally isolated from A. ochraceus. Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide in vitro. Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 µM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 µM, respectively).
| Supplier | BOC Sciences |
|---|---|
| Product # | 360765-75-9 |
| Pricing | Inquire |
| Cas | 360765-75-9 |
| Molecular Weight | 891.02 |
| Molecular Formula | C52H54N6O8 |
| Canonical SMILES | CC1(C=CC2=C(O1)C=CC3=C2N(C4=C3C5C67C(C4(C)C)CC8(CCCN8C6=O)C(=O)N7C9C51C2=C(C3=C(C=C2)OC(C=C3)(C)C)[N+](=C1C(C1C92C(=O)N3CCCC3(C1)C(=O)N2)(C)C)[O-])O)C |