TBK1/NAK (E8I3G) Rabbit Antibody (BSA and Azide Free)

Supplier CD BioSciences
Product # AMA-0570
Pricing 100 µg, Inquire
Product Category Antibodies
Application WB, IF, F
Reactivity Human, Mouse, Rat
Host Rabbit
Gene ID 29110
UniProt ID
Source/Isotype Rabbit IgG
MW (Target) 84 kDa
Storage Store at -20°C. Do not aliquot the antibody.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TBK1/NAK protein.
Background TBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct phosphorylation TBK1 was identified through association with the TRAF binding protein, TANK, and found to function upstream of NIK and IKK in the activation of NF-κB TBK1 induces IκB degradation and NF-κB activity through IKKβ. TBK1 may mediate IKK and NF-κB activation in response to growth factors that stimulate PKCε activity TBK1 plays a pivotal role in the activation of IRF3 in the innate immune response.
Feedback