Encenicline HCl salt
Encenicline, also known as EVP-6124 and MT-4666, is a novel α7 nicotinic acetylcholine receptor agonist that enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens. EVP-6124 improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1490 |
| CAS # | 550999-74-1 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | EVP-6124; EVP 6124; EVP6124; MT-4666; MT4666; MT 4666; Encenicline HCl. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C16H18Cl2N2OS |
| Exact Mass | 356.0517 |
| Molecular Weight | 357.3 |
| Elemental Analysis | C, 53.79; H, 5.08; Cl, 19.84; N, 7.84; O, 4.48; S, 8.97 |
| IUPAC/Chemical Name | (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride. |
| InChi Key | OIJYTJGIDVTCFF-ZOWNYOTGSA-N |
| InChi Code | InChI=1S/C16H17ClN2OS.ClH/c17-12-3-1-2-11-8-14(21-15(11)12)16(20)18-13-9-19-6-4-10(13)5-7-19;/h1-3,8,10,13H,4-7,9H2,(H,18,20);1H/t13-;/m0./s1 |
| SMILES Code | O=C(C1=CC2=CC=CC(Cl)=C2S1)N[C@H]3CN4CCC3CC4.[H]Cl |
| Appearance | white to off-white solid powder |
| Purity | >95% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |