PBIT
PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B.
Supplier | BOC Sciences |
---|---|
Product # | 2514-30-9 |
Pricing | Inquire |
Cas | 2514-30-9 |
Molecular Weight | 241.31 |
Molecular Formula | C14H11NOS |
Canonical SMILES | CC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3S2 |