RC-3095
RC-3095 is a gastrin-releasing peptide receptor antagonist, synergizes with gemcitabine to inhibit the growth of human pancreatic cancer CFPAC-1 in vitro and in vivo. RC-3095 inhibit the growth of human glioblastomas in vitro and in vivo. RC3095 inhibits tumor growth and decrease the levels and mRNA expression of epidermal growth factor receptors in H-69 small cell lung carcinoma.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD348 |
| CAS # | 138147-78-1 |
| Pricing | Customizable size, Inquiry |
| Synonym | RC3095; RC-3095; RC 3095; Amino acid sequences: (D-TPI6, LEU13 y(CH2-NH)-LEU14)BOMBESIN (6-14). |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C56H79N15O9 |
| Exact Mass | 1105.61852 |
| Molecular Weight | 1106.32 |
| Elemental Analysis | C, 60.80; H, 7.20; N, 18.99; O, 13.02 |
| IUPAC/Chemical Name | (S)-N1-((2S,5S,8S,14S,17S,20S)-14-((1H-imidazol-5-yl)methyl)-20-carbamoyl-1-(1H-indol-3-yl)-17-isobutyl-8-isopropyl-5,22-dimethyl-3,6,9,12,15-pentaoxo-4,7,10,13,16,19-hexaazatricosan-2-yl)-2-((R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamido)pentanediamide |
| InChi Key | IUYCRRDHLJIJBB-QAGBKCHLSA-N |
| InChi Code | InChI=1S/C56H79N15O9/c1-29(2)18-35(25-61-42(50(58)74)19-30(3)4)66-55(79)45(21-34-24-59-28-64-34)68-48(73)27-63-56(80)49(31(5)6)71-51(75)32(7)65-54(78)44(20-33-23-60-39-14-10-8-12-36(33)39)70-52(76)41(16-17-47(57)72)69-53(77)43-22-38-37-13-9-11-15-40(37)67-46(38)26-62-43/h8-15,23-24,28-32,35,41-45,49,60-62,67H,16-22,25-27H2,1-7H3,(H2,57,72)(H2,58,74)(H,59,64)(H,63,80)(H,65,78)(H,66,79)(H,68,73)(H,69,77)(H,70,76)(H,71,75)/t32-,35-,41-,42-,43+,44-,45-,49-/m0/s1 |
| SMILES Code | O=C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC1=CN=CN1)C(N[C@@H](CC(C)C)CN[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)[C@@H](NC([C@H]4CC5=C(CN4)NC6=C5C=CC=C6)=O)CCC(N)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |