glutaminyl-tRNA synthase (glutamine-hydrolysing)
In systems lacking discernible glutamine-tRNA ligase (EC 6.1.1.18), glutaminyl-tRNAGln is formed by a two-enzyme system. In the first step, a nondiscriminating ligase (EC 6.1.1.24, glutamate-tRNAGln ligase) mischarges tRNAGln with glutamate, forming glutamyl-tRNAGln. The glutamyl-tRNAGln is not used in protein synthesis until the present enzyme converts it into glutaminyl-tRNAGln (glutamyl-tRNAGlu is not a substrate for this reaction). Ammonia or asparagine can substitute for the preferred substrate glutamine.
| Supplier | Creative Enzymes |
|---|---|
| Product # | EXWM-5810 |
| Pricing | 100 ug, contact supplier for pricing |
| CAS | 52232-48-1 |