Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment
Recombinant Human Antibody is capable of binding to NOTCH1 NRR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-NOTCH1 NRR fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-NOTCH1 NRR proteins fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody holds the promise of simultaneously targeting cancers by directly inhibiting cancer cell growth and disrupting tumour angiogenesis.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PFBL-660 |
| Pricing | Inquiry |
| Host | Human |
| Target | NOTCH1 |
| Species Reactivity | Human |
| Type | Human Fab |
| Applications | ELISA |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |