JP-1302 HCl
JP 1302 dihydrochloride is a α2C-adrenoceptor antagonist that displays ~ 50-fold selectivity over other α2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human α2C, α2B, α2D and α2A subtypes respectively). JP 1302 dihydrochloride potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD914 |
| CAS # | 1259314-65-2 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | JP 1302 dihydrochloride; JP-1302 HCl; JP1302; JP-1302; JP 1302. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C24H26Cl2N4 |
| Molecular Weight | 441.4 |
| Elemental Analysis | C, 65.31; H, 5.94; Cl, 16.06; N, 12.69 |
| IUPAC/Chemical Name | N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinamine dihydrochloride |
| InChi Key | VVZOADYFJAJZGL-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C24H24N4.2ClH/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24;;/h2-13H,14-17H2,1H3,(H,25,26);2*1H |
| SMILES Code | CN1CCN(C2=CC=C(NC3=C(C=CC=C4)C4=NC5=CC=CC=C53)C=C2)CC1.[H]Cl.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |