PIK-III
PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively.
Supplier | Selleck Chemicals |
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Product # | S7683 |
Sku # | S7683-25mg |
Pricing | 25mg, $697.00 |
Citations for this product:
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bioRxiv - Microbiology 2022Quote: ... 5 μM of PIK-III inhibitor (Selleck Chemicals, S7683) or 100nM of Bafilomycin A1 (Sigma-Aldrich B1793 ...