Polyunsaturated Fatty Acid 5-Lipoxygenase (ALOX5) Antibody

ALOX5 Antibody is a Rabbit Polyclonal antibody against ALOX5. This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Supplier Abbexa Ltd.
Product # abx001770-200UL
Pricing 200 µl USD $696.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IHC, IF/ICC
UniProt Primary AC P09917
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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