Mibampator
Mibampator, also known as LY-451395, is an AMPA receptor potentiator under development for agitation/aggression in Alzheimer's disease. Patients treated with LY451395 did not show a statistically significant separation from patients taking placebo on the Alzheimer's Disease Assessment Scale-Cognitive Subscale, the primary outcome measure.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1561 |
| CAS # | 375345-95-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | LY-451395; LY 451395; LY451395; Mibampator |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H30N2O4S2 |
| Exact Mass | 438.1647 |
| Molecular Weight | 438.601 |
| Elemental Analysis | C, 57.51; H, 6.89; N, 6.39; O, 14.59; S, 14.62 |
| IUPAC/Chemical Name | (R)-N-(2-(4'-(2-(methylsulfonamido)ethyl)-[1,1'-biphenyl]-4-yl)propyl)propane-2-sulfonamide |
| InChi Key | ULRDYYKSPCRXAJ-KRWDZBQOSA-N |
| InChi Code | InChI=1S/C21H30N2O4S2/c1-16(2)29(26,27)23-15-17(3)19-9-11-21(12-10-19)20-7-5-18(6-8-20)13-14-22-28(4,24)25/h5-12,16-17,22-23H,13-15H2,1-4H3/t17-/m0/s1 |
| SMILES Code | CC(S(=O)(NC[C@@H](C1=CC=C(C2=CC=C(CCNS(=O)(C)=O)C=C2)C=C1)C)=O)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |