2-oxoglutarate carboxylase

A biotin-containing enzyme that requires Mg2+ for activity. It was originally thought that this enzyme was a promoting factor for the carboxylation of 2-oxoglutarate by EC 1.1.1.41, isocitrate dehydrogenase (NAD+), but this has since been disproved. The product of the reaction is unstable and is quickly converted into isocitrate by the action of EC 1.1.1.41.

• Supplier: Creative Enzymes
• Product #: EXWM-5818
• CAS: 60382-75-4