Arrestin Beta 1 (ARRB1) Antibody
Members of ARRB1/beta-ARRB1 protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-ARRB1 system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of ARRB1 have been described, however, their exact functions are not known.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx026552-80UL |
| Pricing | 80 µl USD $290.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| UniProt Primary AC | P49407 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |