Human Brain Microvascular Endothelial Cells

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Human Brain Microvascular Endothelial Cells (HBMECs), derived from the human brain, are a specific type of brain endothelial cells that play a crucial role in forming the blood-brain barrier (BBB). They prevent the entry of soluble and cellular substances from the blood into the brain and protect it against toxins and immune cells. These brain microvascular endothelial cells have the ability to display cell adhesion molecules on their surface, which control the migration of leukocytes into the brain. Nevertheless, when there are host-pathogen interactions outside the cells, it can activate calcium signaling within the endothelial cells, leading to the penetration of pathogens through the BBB.


Human Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from normal human brain cortical tissue. Each vial contains at least 5×10^5 cells per ml and is delivered frozen.
Supplier Ace Therapeutics
Product # BBM-C-122
Pricing Inquiry
Product Category Primary Cells
Species Human
Applications Human brain microvascular endothelial cells can be used to study the molecular and cellular properties of the blood-brain barrier, or in vitro can be used as the model of the blood-brain barrier (BBB) to study neurological diseases.
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Source Brain
Recommended Medium It is recommended to use Human Brain Microvascular Endothelial Cells Medium Kit for culturing in vitro.
Cell Type Endothelial
Disease Normal
Quality Control Human Brain Microvascular Endothelial Cells test negative for bacteria, yeast, fungi, and mycoplasma.
Shipping and Storage
  • Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage.
  • Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended.
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