Ro-3306
RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with Ki of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7747 |
| Sku # | S7747-10mM/1mL |
| Pricing | 10mM/1mL, $139.00 |
Citations for this product:
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bioRxiv - Molecular Biology 2021Quote: ... abl pre-B cells were treated with 10 μM RO-3306 (Selleck Chemicals, #S7747) overnight ...
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bioRxiv - Cell Biology 2021Quote: ... RO-3306 (Selleck Chemicals, catalog # S7747), Ipatasertib (RG7440 ...
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bioRxiv - Cell Biology 2022Quote: ... 9 μM RO-3306 (Selleck Chemicals, S7747) was added to the media for 20 hours at 37 °C ...
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bioRxiv - Cancer Biology 2022Quote: ... PBMCs were synchronized in G2 in by overnight incubation with 5 μM RO-3306 (Selleck Chemicals, S7747). Cell cycle arrest was released by washing cells twice in PBS ...
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bioRxiv - Molecular Biology 2023Quote: ... Afterwards they were supplemented with 10 μM of the CDK1 inhibitor RO-3306 (S7747, Selleck Chemicals) and incubated for 6 h ...
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bioRxiv - Cell Biology 2023Quote: ... 7 µM RO3306 (CDK1 inhibitor; Selleck chemicals #S7747) was added and cells were incubated for 6 hours ...