RFRP 3 (human)
RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization.
Supplier | BOC Sciences |
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Product # | BAT-015271 |
Pricing | Inquire |
Cas | 311309-27-0 |
Molecular Weight | 969.15 |
Molecular Formula | C45H72N14O10 |
Canonical SMILES | CC(C)CC(C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(C(C)C)N |