Lofepramine hydrochloride
Lofepramine is an antidepressant; serotonin and norepinephrine re-uptake inhibitor (SNRI). A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE. Lofepramine is a third generation tricyclic antidepressant utilized throughout Europe and Japan for the treatment of major depression.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD970 |
| CAS # | 26786-32-3 |
| Pricing | Customizable size, Inquiry |
| Synonym | Lofepramine hydrochloride; DB-2182; WHR 2908A; WHR-2908A; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H28Cl2N2O |
| Exact Mass | 454.1579 |
| Molecular Weight | 455.423 |
| Elemental Analysis | C, 68.57; H, 6.20; Cl, 15.57; N, 6.15; O, 3.51 |
| IUPAC/Chemical Name | 4'-Chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenone monohydrochloride |
| InChi Key | ZWZIQPOLMDPIQM-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C26H27ClN2O.ClH/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29;/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3;1H |
| SMILES Code | O=C(C1=CC=C(Cl)C=C1)CN(CCCN2C3=CC=CC=C3CCC4=CC=CC=C42)C.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |