Amisulpride free base
Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In Italy, it is also used as a treatment for dysthymia. It was introduced by Sanofi-Aventis in the 1990s. Its patent had expired by 2008 and hence generic formulations are now available.Amisulpride function primarily as a D2 and D3 receptor antagonist. It has high affinity for these receptors with dissociation constants of 2.2 nM and 2.4 nM, respectively. Although standard doses used to treat psychosis inhibit dopaminergic neurotransmission, low doses preferentially block inhibitory pre-synaptic autoreceptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1365 |
| CAS # | 71675-85-9 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | Solian; Aminosultopride; Deniban; Amisulprida; Amazeo; Amipride; Amival; Soltus; Sulpitac; Sulprix |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C17H27N3O4S |
| Exact Mass | 369.17223 |
| Molecular Weight | 369.48 |
| Elemental Analysis | C, 55.26; H, 7.37; N, 11.37; O, 17.32; S, 8.68 |
| IUPAC/Chemical Name | 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide |
| InChi Key | NTJOBXMMWNYJFB-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) |
| SMILES Code | CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |