Imatinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15463-1 g |
| CAS # | 152459-95-5 |
| Pricing | 1 g, USD $132.0 |
| Synonyms | STI571; CGP-57148B |
| MWt | 493.6 |
| Formula | C₂₉H₃₁N₇O |
| Biological Activity | Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5]. |
| Purity | 99.54% |