Elzasonan citrate
Elzasonan citrate is a selective 5-HT1B and 5-HT1D receptor antagonist for the treatment of depression. By preferentially blocking 5-HT1B and 5-HT1D autoreceptors, Elzasonan is thought to enhance serotonergic innervations originating from the raphe nucleus, thereby improving signaling to limbic regions like the hippocampus and prefrontal cortex and ultimately resulting in antidepressant effects.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD843 |
| CAS # | 361343-20-6(Elzasonan Citrate) ; 220322-05-4 (Elzasonan hydrochloride) |
| Pricing | Customizable size, Inquiry |
| Synonym | Elzasonan citrate; CP-448,187-10;UNII-67JE11VN82; Elzasonan citrate [USAN]. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C28H31Cl2N3O8S |
| Molecular Weight | 640.53 |
| Elemental Analysis | C, 52.50; H, 4.88; Cl, 11.07; N, 6.56; O, 19.98; S, 5.01 |
| IUPAC/Chemical Name | (2Z)-4-(3,4-dichlorphenyl)-2-(2-(4-methylpiperazin-1-yl)benzylidene)thiomorpholin-3-one citrate (1:1) |
| InChi Key | FIXQLYVNGQBUAP-UXTSPRGOSA-N |
| InChi Code | InChI=1S/C22H23Cl2N3OS.C6H8O7/c1-25-8-10-26(11-9-25)20-5-3-2-4-16(20)14-21-22(28)27(12-13-29-21)17-6-7-18(23)19(24)15-17;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-7,14-15H,8-13H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b21-14-; |
| SMILES Code | CN1CCN(CC1)c2ccccc2\C=C\3/SCCN(C3=O)c4ccc(Cl)c(Cl)c4.OC(=O)CC(O)(CC(=O)O)C(=O)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |