Ilginatinib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19631B-5 mg |
| CAS # | 1239358-85-0 |
| Pricing | 5 mg, USD $285.0 |
| Synonyms | NS-018 hydrochloride |
| MWt | 425.89 |
| Formula | C₂₁H₂₁ClFN₇ |
| Biological Activity | Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM). |
| Purity | 98.02% |