Rapastinel
Rapastinel, also known as GLYX 13 and BV 102, is a monoclonal antibody-derived tetrapeptide that acts as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD334 |
| CAS # | 117928-94-6 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | GLYX-13; GLYX 13; GLYX13; BV-102; BV102; BV 102; TPPT-amide; Rapastinel |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C18H31N5O6 |
| Exact Mass | 413.2274 |
| Molecular Weight | 413.48 |
| Elemental Analysis | C, 52.29; H, 7.56; N, 16.94; O, 23.22 |
| IUPAC/Chemical Name | (S)-1-(L-threonyl-L-prolyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)pyrrolidine-2-carboxamide |
| InChi Key | GIBQQARAXHVEGD-BSOLPCOYSA-N |
| InChi Code | InChI=1S/C18H31N5O6/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27)/t9-,10-,11+,12+,13+,14+/m1/s1 |
| SMILES Code | C[C@@H](O)[C@@H](C(N)=O)NC([C@H]1N(C([C@H]2N(C([C@H]([C@H](O)C)N)=O)CCC2)=O)CCC1)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, DMF, and ethanol |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO, DMF, and ethanol |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |