Afatinib
Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.
Supplier | Selleck Chemicals |
---|---|
Product # | S1011 |
Sku # | S1011-50mg |
Pricing | 50mg, $337.00 |