Rhosin hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12646-10 mM * 1 mL |
| CAS # | 1281870-42-5 |
| Pricing | 10 mM * 1 mL, USD $462.0 |
| Biological Activity | Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis[1][2]. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability[3]. |
| Purity | 99.93% |
| MWt | 394.86 |
| Formula | C₂₀H₁₉ClN₆O |