SR-12062
SR-12062 is a full agonists of the neurotensin receptor 1 (NTSR1). SR-12062 have an EC50 of 2 μM at NTSR1 with full agonist behaviour (Emax=100%), showing a higher efficacy and ∼90-fold potency improvement compared to parent compound 1 (EC50=178 μM; Emax=17%).
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1709 |
| CAS # | 1623019-77-1 |
| Pricing | Customizable size, Inquiry |
| Synonym | SR-12062; SR 12062; SR12062; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C25H25N3O3 |
| Exact Mass | 415.1896 |
| Molecular Weight | 415.493 |
| Elemental Analysis | C, 72.27; H, 6.07; N, 10.11; O, 11.55 |
| IUPAC/Chemical Name | (2-(5-(quinolin-3-yl)-1H-indol-1-yl)acetyl)-L-leucine |
| InChi Key | FPIZUBHJQMKCPU-QFIPXVFZSA-N |
| InChi Code | InChI=1S/C25H25N3O3/c1-16(2)11-22(25(30)31)27-24(29)15-28-10-9-19-12-17(7-8-23(19)28)20-13-18-5-3-4-6-21(18)26-14-20/h3-10,12-14,16,22H,11,15H2,1-2H3,(H,27,29)(H,30,31)/t22-/m0/s1 |
| SMILES Code | O=C(N[C@@H](CC(C)C)C(O)=O)CN1C=CC2=C1C=CC(C3=CC4=CC=CC=C4N=C3)=C2 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |