Plasmepsin V FRET Substrate

Supplier Creative Peptides
Product # X21187
Pricing Inquire
MolecularWeight 1751.1
Sequence
  • One Letter Code: Dabcyl-LNKRLLHETQ-EDANS
  • Three Letter Code: Dabcyl-Leu-Asn-Lys-Arg-Leu-Leu-His-Glu-Thr-Gln-EDANS
Storage -20°C
Explanation This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.
Reference Russo, I. et al. Nature 463, 632 (2010).
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