| Supplier |
Creative Peptides |
| Product # |
10-101-112 |
| CAS # |
189691-06-3 |
| Pricing |
Inquire
|
| Synonyms |
(Ac-Nle4, Asp5, D-Phe7, Lys10)-cyclo-α-MSH (4-10); PT-141; PT 141; PT141
|
| MolecularFormula |
C50H68N14O10
|
| MolecularWeight |
1025.18
|
| Sequence |
Three Letter Code: Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys);Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH
|
| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
| Explanation |
Bremelanotide, formerly known as PT-141, is a peptide drug. Bremelanotide acts as a non-selective agonist of all of the melanocortin receptors except MC2.
|
| ChemicalName |
(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxylic acid
|
| Application |
Erectile dysfunction & Female sexual dysfunction & Hemorrhagic shock & Reperfusion injury
|
| Activity |
Agonist
|
| InChI |
InChI=1S/C50H68N14O10/c1-3-4-16-35(58-29(2)65)43(67)64-41-25-42(66)54-20-11-10-18-37(49(73)74)60-46(70)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(68)36(19-12-21-55-50(51)52)59-45(69)38(22-30-13-6-5-7-14-30)61-47(71)40(63-48(41)72)24-32-27-53-28-57-32/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25H2,1-2H3,(H,53,57)(H,54,66)(H,58,65)(H,59,69)(H,60,70)(H,61,71)(H,62,68)(H,63,72)(H,64,67)(H,73,74)(H4,51,52,55)/t35-,36-,37-,38+,39-,40-,41-/m0/s1
|
| InChIKey |
FFHBJDQSGDNCIV-MFVUMRCOSA-N
|
| CanonicalSMILES |
CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C
|
| IsomericSMILES |
CCCC[C@@H](C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C
|
| Appearance |
White Powder
|
| Target |
Melanocortin Receptor
|