Embelin
Supplier | MedChemExpress |
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Product # | HY-17473-10 mM * 1 mL |
CAS # | 550-24-3 |
Pricing | 10 mM * 1 mL, USD $73.0 |
Synonyms | Embelic acid; Emberine; NSC 91874 |
MWt | 294.39 |
Formula | C₁₇H₂₆O₄ |
Biological Activity | Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells[1][2][3]. |
Purity | 98.75% |