Human Anti-ECD Recombinant Antibody (clone mAb1)
Recombinant Human Antibody (mAb1) is capable of binding to ECD, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ECD mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ECD proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody inhibits glucagon receptor by occluding a surface extending across the entire hormone-binding cleft.
Supplier | Creative Biolabs |
---|---|
Product # | PABL-459 |
Pricing | Inquiry |
Host | Human |
Target | ECD |
Species Reactivity | Human |
Type | Human IgG |
Applications | ELISA, WB, FuncS |
Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |