Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody

SNCG (also designated gamma synuclein or breast cancer-specific protein 1),with 127-amino acid protein (about 14kDa), belongs to the synuclein family, which also includes alpha and beta synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

• Supplier: Alfa Cytology
• Product #: BE0086