Anti-Human GAD2 Recombinant Antibody
Recombinant Human monoclonal antibody expressed in CHO binding to Human GAD2. GAD65Ab are common in healthy individuals, but masked by epitope-specific anti-idiotypic antibodiess. GAD65Ab may have a pathogenic role in the disease process in patients with Stiff Person Syndrome (SPS). GAD65Ab in SPS patients inhibit the enzyme's activity and result in a deficit in the major inhibitory neurotransmitter GABA, possibly causing clinical symptoms such as muscle spasms and stiffness.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-297CL |
| Pricing | Inquiry |
| Host | Human |
| Target | GAD2 |
| Species Reactivity | Human |
| Type | Antibody |
| Storage | Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C. |