| Supplier |
Creative Peptides |
| Product # |
X21153 |
| Pricing |
Inquire
|
| MolecularWeight |
2285.7
|
| Sequence |
- One Letter Code: KKARFSRFAGSSPSQSSMVAR
- Three Letter Code: H-Lys-Lys-Ala-Arg-Phe-Ser-Arg-Phe-Ala-Gly-Ser-Ser-Pro-Ser-Gln-Ser-Ser-Met-Val-Ala-Arg-OH
|
| Storage |
-20°C
|
| Explanation |
This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4, derived from the IRAK-1 activation loop peptide amino acids 360 to 380. This peptide sequence contains Ser-376, one of the primary phospho-acceptor residues of IRAK-1. IRAK-4 phosphorylates IRAK-1 as a key step in regulation of inflammatory signaling pathways.
|
| Reference |
Hekmat-Nejad, M. et al. Biochem 49, 1495 (2010).
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