TAK-653
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induced Ca2+ influx in hGluA1i-expressing CHO cells through structural interference at Ser743 in GluA1,
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1195 |
| CAS # | 1358751-06-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | TAK-653; TAK653; TAK 653; NBI-1065845; NBI1065845; NBI 1065845; osavampator |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H23N3O3S |
| Exact Mass | 373.146 |
| Molecular Weight | 373.471 |
| Elemental Analysis | C, 61.10; H, 6.21; N, 11.25; O, 12.85; S, 8.58 |
| IUPAC/Chemical Name | 9-(4-(cyclohexyloxy)phenyl)-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide |
| InChi Key | PXJBHEHFVQVDDS-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H23N3O3S/c1-14-13-22-11-12-26(23,24)21-19(22)18(20-14)15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3 |
| SMILES Code | CC1=CN(CC2)C(C(C3=CC=C(OC4CCCCC4)C=C3)=N1)=NS2(=O)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |