Wortmannin
Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity.
Supplier | Selleck Chemicals |
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Product # | S2758 |
Sku # | S2758-5mg |
Pricing | 5mg, $110.00 |
Citations for this product:
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bioRxiv - Systems Biology 2021Quote: ... and wortmannin (Selleck Chemicals, S2758) were used for treating the cells ...
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bioRxiv - Cancer Biology 2024Quote: ... Wortmannin 35nM (Selleck chemical, S2758), Rapamycin 100nM (Sigma-Aldrich ...